Expert System for Decision Support in
Drug Therapy, PHARM-2
S. Butko, V. Olchanski, A. Petrovski, V. Rodionov, S. Efuni
MEDINFO 86, 5th World Congress on Medical Informatics
R.Salamon, B.Blum, M.Jorgensen (Editors)
Elsevier Science Publishers B.V. (North-Holland)
IFIP-IMIA, 1986. p.495-496
a fragment of the report
The choice of treatment is done by using a pharmacology data base
constructed with the group expert assessments techniques. The
experimental studies have revealed certain psychological background of
the adequate drug therapy by physicians. These psychological
peculiarities have been formalized and implemented in a computer
program. The choice of drug therapy is carried out in a dialog with
computer which provides for:
- a minimal number of the prescribed drugs for treatment of very
complicated emergency cases;
- making the choice faster under the time pressure;
- exclusion of errors due to a narrowed thinking scope under pressure;
- the look-up of several different options for treatment;
- easy update of the pharmacological data base;
- application and implementation in various real-life conditions;
- application as a training tool for doctors and students;
- use as a reference.
The system utilizes a drug incompatibilities data base. Working in the
dialog mode, the system inhibits the choice of incompatible drugs while
the occurence of undesirable or unusual drug combinations is announced
with a special warning. The user may reject any component of such an
undesirable combination. A special routine may give the explanation of
the given warning.
For keeping record, the dialog may be printed out.
The theory for developing this system is described in the following
papers:
- S. Butko et al. PHARMREC - Un algorithme specialise pour le choix d'un
traitement pharmacologique assiste par ordinateur. Innovation et
technologie en biologie et medicine. Vol.5, No.4, 1984, p.400-6 (in
English), Lille, France.
- S. Butko et al. Un modele descriptif de la prise des decisions
pharmacotherapeutiques. Innovation et technologie en biologie et
medicine. Vol.7, No.2, 1986. p.167-176. (in English), Lille, France.
- S. Butko et al. Interactive multicriterial choice of variants in
problems with weak constraints. International Journal of Systems
Science. Vol.19, No.1, p.65-76, 1988.
- S. Butko et al. Drug Therapies Efficiency Measurement for an Expert
System Knowledge Base. IEEE Engineering in Medicine & Biology Society
10th Annual International Conference, November 1988, New Orleans, USA.
- S. Butko et al. Multiple Drug Therapy Selection. MEDINFO-89, 6th World
Congress on Medical Informatics. Beijing-Singapore, 1989.
The Pharm-2 System is a chapter in Ph.D. dissertation of Sergei Butko defended
at the Moscow Institute of Physics and Technology and has been implemented in
an ER at the National Research Center for Surgery in Moscow.
The Pharm-2 System has been marketed by MEDINCO Associates of Moscow. For other
products of MEDINCO see XDIS: Diagnostic Advisory System
With questions email
Vlad Olchanski, PhD:
volchans@vcu.edu
3-26-96